From Aaron Siri:
FDA has licensed three bird flu (H5N1) vaccines:
- Sanofi (National Stockpile). Licensed for adults based on trial in which only 103 adults vaccinated and 48 received placebo; worse, there were four serious adverse events in the vaccine group.
- ID Biomedical. In the adult trial, the vaccine group had four times the rate of new immune mediated diseases. (The trial for children, 6 months to 17 years, had only 838 children and hence was underpowered.)
- Seqirus. In the adult trial, 0.5% of the vaccinated group died but only 0.1% of the placebo group died. (The trial for children, 6 months to 17 years, had only 329 children and hence was underpowered.)
If you plan to get pricked, be informed.
Sanofi: https://www.fda.gov/media/74534/download
ID Biomedical: https://www.fda.gov/media/87479/download
Seqirus: https://www.fda.gov/media/135020/download
12:08 pm on July 4, 2024