Should You Worry About Genetically Modified Food?
by
Mark Sisson
Mark’s Daily Apple
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A new study
came out last month out of France. In it, researchers found that
rats on diets consisting of 11%, 22%, and 33% Roundup-resistant
genetically modified corn developed far more mammary tumors than
control rats on non-GMO corn diets. GMO diet rats died earlier and
in greater numbers. Why is this study notable amidst all the other
studies that seem to show the safety of GMOs? Well, it’s one
of the few long term GMO feeding studies, lasting a full two years,
which, to a rat, is the equivalent
of 60 of our human years. The other safety studies which found
no evidence of toxicity in GM foods tend to last just 90 days, or
15 rat years. In other words, the French study studied rats over
the course of an entire lifespan, whereas other studies have looked
at rats for a relatively brief snippet of their lives. Cancer generally
develops over a lifetime, as you probably know, so this would appear
to be more relevant to human health than the shorter trials.
Of course,
there has been a huge
outcry against the study and its author. Critics have said the
sample sizes (ten rats per group of each sex) were too small, but
judging from the official
guidelines of the Organization for Economic Co-Operation and
Development (OECD), which states that oral toxicity experiments
using rats must use at least 20 animals per group (10 males and
10 females), the French study was just doing what other GMO studies
have done. Even if the sample sizes are inadequate, couldn’t
that be rectified by running a longer, larger, later study to attempt
to replicate its findings?
Obviously,
genetically modified organisms (GMOs) are a testy subject, and people
from both sides of the argument make articulate, seemingly logical
points about why the other side is completely and utterly wrong.
I don’t claim to have the answer either way, but hopefully
this post will help you make a decision that works for you.
To date, it’s
true that there exists no conclusive hard evidence that GM foods
are dangerous to people. There are no human feeding trials, and,
because GM foods aren’t labeled (at least in the United States)
and people don’t know what they’re eating enough to
give an accurate account of their food intake, epidemiological studies
on the effects are impossible to conduct. You can’t ask people
how often they’ve eaten GM foods over the past ten years if
the average person doesn’t even know what
GMOs are. There are some animal studies, like the one mentioned
above, but there have been mixed results, with some independent
studies showing potentially problematic differences in health outcomes
between GMOs and non-GMOs, and industry studies showing no significant
differences.
Personally,
I’m not so worried about a fish gene being put into a tomato,
or insect genes in strawberries on their own merits. I’m worried
about whether that particular gene codes for the production of a
lectin that might harm the person that eats the crop. I’m
worried about the amount of Roundup that farmers will therefore
spray on the crops, having been given carte blanche to use gallons
of the stuff. I’m worried about the Roundup-resistant
weeds and Bt-resistant bugs that are popping up in response
to all the Roundup being applied and Bt-crops being used. I’m
worried about the more toxic herbicides
and pesticides being used to take care of these new superweeds and
superbugs. Didn’t a wise man once say that “Life
finds a way“? Though he was a fictional character talking
about the unintended consequences of using frog DNA to “plug”
the holes in dinosaur DNA, I think he was right.
A lot of people
are worried about the potential of unintended effects to arise.
I think John Hagelin said it well in his
statement to the EPA:
Numerous
eminent molecular biologists recognize that DNA is a complex nonlinear
system and that splicing foreign genes into the DNA of a food-yielding
organism can cause unpredictable side effects that could harm
the health of the human consumer. Yet, the genetic engineering
of our food – and the widespread presence of genetically
altered foods in American supermarkets – is based on the
premise that the effects of gene-splicing are so predictable that
all bioengineered foods can be presumed safe unless proven otherwise.
Take a recent
example of transgenic modification applied to cassava, a staple
starchy tuber for millions (if not billions) of people across the
globe. This is the stuff that’s high in cyanide, requires
extensive processing to remove said cyanide, and has an extremely
paltry protein content (the lowest of all staples foods, in fact).
Transgenic
insertion of a gene into the plant increased the protein content
four-fold and reduced the cyanide content by up to 55%, turning
a decent staple into a fantastic, protein-rich one – at least
on paper. The increased protein came from a novel chimeric storage
protein called zeolin, which was cobbled
together using zein (from corn) and phaseolin (from beans, used
in “carb
blocker” products). For someone who relies on cassava
for, well, everything, the increased protein is welcome and perhaps
even necessary. But zein (also known as corn gluten) is a prolamine,
a type of plant protein that many people have trouble digesting,
as well as an herbicide in its own right (PDF).
Wheat gluten
is another (in)famous prolamine. Phaseolin is a “carb blocker”;
it literally reduces your absorption and digestion of glucose. The
zeolin may not have the same properties as zein or phaseolin, and
even if it did, those properties may be worth it if it’s the
best source of protein in the area, but I think this example shows
that genetic engineering has the potential to have unintended effects.
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October 19, 2012
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